THE POLYMER SOCIETY OF KOREA

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세션명 Korea-Australia Joint Symposium: Functional Macromolecules for Advanced Applications (English)
발표장 제8회장
논문코드 1L8-5
발표일 2021-10-21
발표시간 16:00-16:25
논문제목 Stealth Poly(2-oxazoline) Nanoparticles for Biomedical Applications
발표자 Kristian Kempe
발표자 소속 Monash University
저자 Kristian Kempe
소속 Monash University
논문초록 We report the preparation of functional and biocompatible poly(2-oxazoline) (POx)-based nanoparticles of different morphologies and discuss their bio-nano interactions. POx are a highly functional polymer class, which provides access to tailor-made polymers with tuneable physicochemical properties. The water-soluble variants are highly biocompatible, non-immunogenic and show a stealth behavior. Thus, they are highly interesting as shell materials for diverse nanoparticles used in a biological context. In this presentation we will highlight our recent efforts in fabricating spherical and rod-shaped POx nanoparticles through, e.g. emulsion processes, surface coatings of inorganic nanoparticles and crystallization-driven self-assembly (CDSA). The potential to modulate the interaction of these nanoparticles with biological entities through variation of size, shape and polymer/surface modifications will be discussed.